Antioxidant and Antibacterial Activity of Acetone Extract of Javanese Pepper Fruit (Piper retrofractum Vahl.)

Iqbal Musthapa, Gun Gun Gumilar

Sari


Javanese Pepper (Piper retrofractum Vahl.) has been known as economically valuable herb and has been traditionally used as folk medicine (jamu) against various kinds of health disorders, such as bronchitis, fever, tuberculosis, diarhea, as mouthwash, and aphrodisiac. Until now, there is no report about antioxidant and antibacterial activity of acetone extract of Javanese pepper fruit originated from West Java. Therefore, this study analyzes antioxidant and antibacterial activities of acetone extract of Javanese pepper fruit originated from West Java. Antioxidant activity determined by DPPH (1,1-diphenyl-2-picrilhydrazil) radical scavenging method, while antibacterial activity determined by agar diffusion method with Eschericia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus mutans as test bacterials. Acetone extract of Javanese pepper fruit is proven to possess antioxidant activity with IC50 value of 825 ppm. Meanwhile, antibacterial activity determination of acetone extract of Javanese pepper fruit shows inhibition zone on Staphylococcus aureus, but no inhibition found for another tested bacterials.

Kata Kunci


Javanese Pepper; Antioxidant; Antibacterial

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Referensi


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