Phytochemical Profile and Anticancer Activity from Medicinal Plants Against Melanoma Skin Cancer: A Review

Adryan Fristiohady, Rathapon Asasutjarit, La Ode Muh. Julian Purnama, Sewan Theeramunkong, Wirhamsah Al-Ramadan, Lidya Agriningsih Haruna, Nur Syifa Rahmatika, Syarul Nataqain Baharum, I. Sahidin

Abstract


Melanoma skin cancer is a malignant melanocyte tumor considered the most invasive and dangerous skin cancer, with an average five-year survival rate of less than 5% after metastasis. Thus, a new strategy for preventing and treating cancer from the natural product is required. Medicinal plants are the potential as an alternative against cancer. This review article aims to determine natural products from medicinal plants which have the potential as an anticancer in melanoma skin cancer in vitro and in vivo. 40 plants have been selected based on the selection criteria for anticancer compounds. In vitro studies showed that the plant can reduce cell viability through cell cycle inhibition and apoptosis induction and inhibit angiogenesis, invasion, and metastasis in human melanoma skin cancer. Therefore, further research is required to explore more plants, especially medicinal plants, their active compounds, and the mechanism of anticancer action to be used as standard herbal medicines.

Keywords


Anticancer activity; Human melanoma skin cancer; Plants

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Abad, M. J., Bedoya, L. M., Apaza, L., and Bermejo, P. The artemisia L. (2012). Molecules (Basel, Switzerland), 17(3), 2542–2566.

Abate, M., Pagano, C., Masullo, M., Citro, M., Pisanti, S., Piacente, S., and Bifulco, M. (2022). Pharmaceuticals, 15(1), 1-16

Abdel-Wahhab K. G. E.-D., Abbas El-Shamy K., Abd El-Zizz El-Beih N., Adly Morcy F., and Abd Elwahid Mannaa F. (2011). Comunicata Scientiae, 2(1), 9-17.

Abdulridha, M. K., Al-Marzoqi, A. H., Al-Awsi, G., Mubarak, S., Heidarifard, M., and Ghasemian, A. (2020). Journal of gastrointestinal cancer, 51(3), 765–773

Abisheva, L. N., Belenovskaya, L. M., Bobileva, N. S., Bikova, O. P., Kondratenkova, T. D., Kudrova (Yakobson) E. L. (2001). Budancev AL, Lesiovskaya EE, editors. SPCPA, St. Petersburg, Russian Federation, 2001, 252-253.

Agarwal, U., Pathak, D.P., Bhutani, R., Kapoor, G., and Kant, R. (2017). nternational Journal of Pharmacognosy and Phytochemical Research, 9(8), 1119-1126.

Ahmed, R., Muralidharan, R., Srivastava, A., Johnston, S. E., Zhao, Y. D., Ekmekcioglu, S., Munshi, A., and Ramesh, R. (2021). Cancers, 13(2), 1–19.

Ali, B. H., Blunden, G., Tanira, M. O., and Nemmar, A. (2008). Food and chemical Toxicology, 46(2), 409-420.

Ali, B. H., Marrif, H., Noureldayen, S. A., Bakheit, A. O., and Blunden, G. (2006). Natural Product Communications, 1, 509-521.

Alonso, J., and Desmarchelier, C. (2005). Buenos Aires, 409–416.

AlQathama, A., Bader, A., Al-Rehaily, A., Gibbons, S., and Prieto, J. M. (2022). European Journal of Integrative Medicine, 49, 102083.

Al-Qathama, A., Gibbons, S., and Prieto, J. M. (2017). Oncotarget, 8(56), 95999.

Al-Youssef, A. H. M., and Hassan, W. H. (2014). International journal of current research in chemistry and pharmaceutical sciences, 1(9), 12-24.

Anmol, R. J., Marium, S., Hiew, F. T., Han, W. C., Kwan, L. K., Wong, A., Khan, F., Sarker, M., Chan, S. Y., Kifli, N., and Ming, L. C. (2021). Journal of Evidence-Based Integrative Medicine, 26, 2515690X211043741.

Aquino, D. S., and García, M. T. A. (2019). Plant Ecol, 220(9), 845–860.

Arakawa, N., Okubo, A., Yasuhira, S., Takahashi, K., Amano, H., Akasaka, T., Masuda, T., Shibazaki, M., and Maesawa, C. (2018). Oncology Letters, 15(2), 2393–2400.

Armoskaite V., Ramanauskim, K., Maruska, A., Razukas, A., Dagilyte, A., Baranauskas, A., and Briedis, V. (2011). Journal of Medicinal Plants Research, 5(5), 811-816.

Asare, G. A., Afriyie, D., Ngala, R. A., Abutiate, H., Doku, D., Mahmood, S. A., and Rahman, H. (2015). Integrative Cancer Therapies, 14(1), 65–74.

Asasutjarit, R., Sooksai, N., Fristiohady, A., Lairungruang, K., Ng, S. F., and Fuongfuchat, A. (2021). Pharmaceutics, 13(8), 1290.

Báez, R., Lopes, M. T., Salas, C. E., and Hernández, M. (2007). Planta Medica, 73(13), 1377–1383.

Bailly, C. (2021). Journal of Ethnopharmacology, 280, 114444.

Banerjee, J., Biswas, S., Madhu, N. R., Karmakar, S. R., and Biswas, S. J. (2014). Journal Pharmacogn Phytochem, 3(1), 207–210.

Bao, T. Q., Li, Y., Qu, C., Zheng, Z. G., Yang, H., and Li, P. (2020). The American journal of Chinese medicine, 48(6), 1353–1368.

Baskar, R., Rajeswari, V., and Kumar, T. S. (2007). Indian Journal of Experimental Biology, 45(5), 480–485.

Bhui, K., Tyagi, S., Srivastava, A. K., Singh, M., Roy, P., Singh, R., and Shukla, Y. (2012). Molecular Carcinogenesis, 51(3), 231-243.

Bociort, F., Macasoi, I. G., Marcovici, I., Motoc, A., Grosu, C., Pinzaru, I., Petean, C., Avram, S., and Dehelean, C. A. (2021). Current Oncology (Toronto, Ont.), 28(6), 5054–5066.

Bonesi, M., Loizzo, M. R., Acquaviva, R., Malfa, G. A., Aiello, F., and Tundis, R. (2017). Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, 16(2), 70–86.

Boukhary, R., Raafat, K., Ghoneim, A. I., Aboul-Ela, M., and El-Lakany, A. (2016). Evidence-Based Complementary and Alternative Medicine: eCAM, 2016, 7178105.

Boumendjel, A., Ronot, X., and Boutonnat, J. (2009). Current Drug Targets, 10(4), 363–371.

Bourhia, M., Laasri, F. E., Aourik, H., Boukhris, A., Ullah, R., Bari, A., Ali, S. S., El Mzibri, M., Benbacer, L., and Gmouh, S. (2019). Evidence-Based Complementary and Alternative Medicine: eCAM, 2019, 7623830.

Burgeiro, A., Bento, A. C., Gajate, C., Oliveira, P. J., and Mollinedo, F. (2013). European Journal of Pharmacology, 705(1-3), 109–118.

Caramelo, D., Pedro, S. I., Marques, H., Simão, A. Y., Rosado, T., Barroca, C., Gominho, J., (2021). Applied Sciences, 11(23), 11331.

Cattaneo, L., Cicconi, R., Mignogna, G., Giorgi, A., Mattei, M., Graziani, G., Ferracane, R., Grosso, A., Aducci, P., Schininà, M. E., and Marra, M. (2015). PloS One, 10(7), e0132439.

Chakraborty, D., and Shah, B. (2011). International Journal of Pharmacy and Pharmaceutical Sciences, 3, 192–199.

Chander, V., Aswal, J. S., Dobhal, R., and Uniyal, D. P. (2017). Journal Phytopharmacol, 6(1), 53-58.

Chang, C. J., Hung, Y. L., Chen, T. C., Li, H. J., Lo, Y. H., Wu, N. L., Chang, D. C., and Hung, C. F. (2021). Biomolecules, 11(7), 1039.

Chen, H. Y., Jiang, Y. W., Kuo, C. L., Way, T. D., Chou, Y. C., Chang, Y. S., and Chung, J. G. (2019a). Environmental Toxicology, 34(4), 434–442.

Chen, J., Huang, C., Liu, F., Xu, Z., Li, L., Huang, Z., and Zhang, H. (2019b). Archives of Medical Science: AMS, 15(4), 1056–1064.

Chen, W. H., Wang, R., and Shi, Y. P. (2010). Journal of Natural Products, 73(8), 1398–1403

Chen, Y., Huang, J. Y., Lin, Y., Lin, I. F., Lu, Y. R., Liu, L. H., and Wang, H. M. D. (2018). Journal of Food Quality, 2018, 1-6.

Chik, W. I., Zhu, L., Fan, L. L., Yi, T., Zhu, G. Y., Gou, X. J., Tang, Y. N., Xu, J., Yeung, W. P., Zhao, Z. Z., Yu, Z. L., and Chen, H. B. (2015). Journal of ethnopharmacology, 172, 44–60.

Choi, E. O., Cho, E. J., Jeong, J. W., Park, C., Hong, S. H., Hwang, H. J., Moon, S. K., Son, C. G., Kim, W. J., and Choi, Y. H. (2017). Biomolecules and Therapeutics, 25(2), 213–221

Choudhary, S., Kaurav, H., Madhusudan, S., and Chaudhary, G. (2021). International Journal for Research in Applied Sciences and Biotechnology, 8(2), 98-106.

Chouni, A., and Paul, S. (2018). Pharmacognosy Journal, 10(1), 9-15.

Chudiwal, A. K., Jain, D. P., and Somani, R. S. (2010). Indian Journal of Natural Products and Resources, 1, 143-149.

Chupin L., Maunu S. L., Reynaud S., Pizzi A., Charrier B., Charrier-El Bouhtoury F., (2015). Industrial Crops and Products, 65, 142-149

Croaker, A., King, G. J., Pyne, J. H., Anoopkumar-Dukie, S., and Liu, L. (2016). International Journal of Molecular Sciences, 17(9), 1414.

Danciu, C., Zupko, I., Bor, A., Schwiebs, A., Radeke, H., Hancianu, M., Cioanca, O., Alexa, E., Oprean, C., Bojin, F., Soica, C., Paunescu, V., and Dehelean, C. A. (2018). International Journal of Molecular Sciences, 19(11), 3624.

Das, S., Das, J., Samadder, A., Boujedaini, N., and Khuda-Bukhsh, A. R. (2012). Experimental biology and medicine (Maywood, N.J.), 237(12), 1433–1448.

de Melo G. A. N., Grespan, R., Fonseca, J. P., Farinha, T. O., Silva, E. L., Romero, A. L., Bersani-Amado, C. A., and Cuman, R. K. (2011). Journal of Medicinal Food, 14(9), 944–946.

de Pascual-Teresa, S., Santos-Buelga, C., and Rivas-Gonzalo, J. C. (2000). Journal of Agricultural and Food Chemistry, 48(11), 5331–5337.

Debnath, B., Singh, W. S., and Manna, K. (2021). Advances in Traditional Medicine, 2021, 1-8.

Dhippayom, T., Kongkaew, C., Chaiyakunapruk, N., Dilokthornsakul, P., Sruamsiri, R., Saokaew, S., and Chuthaputti, A. (2015). Evidence-Based Complementary and Alternative Medicine: eCAM, 2015, 942378.

Dillon, S. L., Shapter, F. M., Henry, R. J., Cordeiro, G., Izquierdo, L., and Lee, L. S. (2007). Annals of Botany, 100(5), 975–989.

Du, Y. Q., Yan, Z. Y., Chen, J. J., Wang, X. B., Huang, X. X., and Song, S. J. (2021). Natural Product Research, 35(7), 1139–1146.

Duan, L., Guo, L., Dou, L. L., Yu, K. Y., Liu, E. H., and Li, P. (2014). Journal of Agricultural and Food Chemistry, 62(46), 11122–11129.

Dutta, N. K., and Panse, M. V. (1962). Indian Journal of Medical Research, 50(5), 732-736.

Eissa, T. F., González-Burgos, E., Carretero, M. E., and Gómez-Serranillos, M. P. (2014). Pharmaceutical Biology, 52(2), 151–156.

El-Askary, H. I., Haggag, M. Y., Abou-Hussein, D. R., Hussein, S. M., and Sleem, A. A. (2017) Iranian Journal of Pharmaceutical Research, 16, 46–57.

El-Fiky, F. K., Abou-Karam, M. A., and Afify, E. A. (1996). Journal of Ethnopharmacology, 50(1), 43-47.

Fraihat, A., Alatrash, L., Abbasi, R., Abu-Irmaileh, B., Hamed, S., Mohammad, M., and Bustanji, Y. (2018). Tropical Journal of Pharmaceutical Research, 17(6), 1081-1086

Gaire, B. P., Moon, S. K., and Kim, H. (2014). Chinese Journal of Integrative Medicine, 20(9), 712–720

Gajalakshmi, S., Vijayalakshmi, S., and Devi, R. V. (2012). International Journal of Pharmacy and Pharmaceutical Sciences, 4(2), 3-6.

George, V. C., Kumar, D. R. N., Suresh, P. K., Kumar, S., and Kumar, R. A. (2013). Asian Pacific Journal of Cancer Prevention, 14(2), 631-637.

Ghasemzadeh Rahbardar, M, and Hosseinzadeh, H. (2020). Iranian Journal of Basic Medical Sciences, 23(9), 1100-1112.

Ghiƫu, A., Pavel, I. Z., Avram, S., Kis, B., Minda, D., Dehelean, C. A., Buda, V., Folescu, R., and Danciu, C. (2021). Analytical cellular pathology (Amsterdam), 2021, 5552664.

Goossens, J. F., Goossens, L., and Bailly, C. (2021). Natural Products and Bioprospecting, 11(4), 365–377.

Gordon, L. G., Leung, W., Johns, R., McNoe, B., Lindsay, D., Merollini, K., Elliott, T. M., Neale, R. E., Olsen, C. M., Pandeya, N., and Whiteman, D. C. (2022). International Journal of Environmental Research and Public Health, 19(6), 3178.

Gull, T., Sultana, B., Bhatti, I.A., and Jamil, A. (2015). International Journal of Agriculture and Biology, 17(4), 726-733.

Gunter, N. V., Teh, S. S., Lim, Y. M., and Mah, S. H. (2020). Frontiers in Pharmacology, 11, 1-20.

Guo, X., Matsidik, R., Ablise, M., Sheng, L. and Abudula, B. (2013a). Journal of Medicinal Plants Research, 7, 173–178.

GUO, X., Rukiya, M. A. T. S. I. D. I. K., Mourboul, A. B. L. I. S. E., SHENG, L., and Abulizi, A. B. U. D. U. L. A. (2013b). Journal of Medicinal Plants Research, 7(5), 173-178.

Guo, Y., Zhang, B. Y., Peng, Y. F., Chang, L. C., Li, Z. Q., Zhang, X. X., and Zhang, D. J. (2022). Molecules, 27(5), 1706.

Guon, T. E., and Chung, H. S. (2016). Journal of the East Asian Society of Dietary Life, 26(3), 207-214.

Gupta R.K., Krishnamurti M., and Parthasarathi J. (1979). Agricultural and Biological Chemistry, 43, 2603–2605.

Gupta, D. K., Aqil, M., Ahad, A., Imam, S. S., Waheed, A., Qadir, A., and Sultana, Y. (2020). Journal of Drug Delivery Science and Technology, 60, 102051.

Gupta, R. (2010). CBS Publishers and Distributors, New Delhi, India, 234, 499-500.

Gürbüz, P., Dokumacı, A. H., Gündüz, M. G., Perez, C., Göger, F., Paksoy, M. Y., Yerer, M. B., and Ömür Demirezer, L. (2021). Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society, 29(3), 236–243.

Hai-yan, Y. A. N., and Li-ming, G. A. O. (2009). Natural Product Research and Development, 21(2), 246–248.

Hamdi, A., Majouli, K., Abdelhamid, A., Marzouk, B., Belghith, H., Chraief, I., Bouraoui, A., Marzouk, Z., and Heyden, Y.V. (2018a). Journal of Ethnopharmacology, 216, 97–103.

Hamdi, A., Viane, J., Mahjoub, M. A., Majouli, K., Gad, M. H. H., Kharbach, M., Demeyer, K., Marzouk, Z., and Heyden, Y.V. (2018b). International Journal of Biological Macromolecules, 106, 1071–1079.

Hammerová, J., Uldrijan, S., Táborská, E., and Slaninová, I. (2011). Journal of dermatological science, 62(1), 22–35.

Han, H. J., Park, S. K., Kang, J. Y., Kim, J. M., Yoo, S. K., and Heo, H. J. (2020). Nutrients, 12(3), 832.

Hayashi, H. and Sudo, H. (2009). Plant Biotechnol, 26, 101–104.

He, S., Wang, S., Liu, S., Li, Z., Liu, X., and Wu, J. (2021). Frontiers in pharmacology, 12, 743837.

Heredia, D., Green, I., Klaasen, J., and Rahiman, F. (2022). Scientifica, 2022, 5793436

Hoffman, T. (2007). Hawaii Medical Journal, 66, 326-327.

Huang, R., Mao, M., Lu, Y., Yu, Q., and Liao, L. (2020). Aging, 12(8), 6966–6980.

Huang, S. H., Hsu, M. H., Hsu, S. C., Yang, J. S., Huang, W. W., Huang, A. C., Hsiao, Y. P., Yu, C. C., and Chung, J. G. (2014). Human and experimental toxicology, 33(3), 270–283.

Hussain, A., Hayat, M.Q., Sahreen, S., Ain, Q., and Bokhari, S.A.I. (2017). Proceedings of the Pakistan Academy of Sciences: B. Life and Environmental Sciences, 54(4), 265–287.

Hwang, S. Y., Chae, J. I., Kwak, A. W., Lee, M. H., and Shim, J. H. (2020). International Journal of Molecular Sciences, 21(18), 6869.

Ibrahim, H., Abdulrahman, E. M., Shok, M., Ilyas, N., Musa, K. Y., and Ukandu, I. (2007). African Journal of Biotechnology, 6(10), 1233-1235.

Ibrahim, H., Abdurahman, E. M., Shok, M., Ilyas, N., and Bolaji, R. (1999). Proceedings of 1st International Workshop on Herbal Medicinal Products, Ibadan, Nigeria, 22-24 November, 1998. University of Ibadan, Department of Pharmacognosy, 217-222.

Jain, S. K., Rajvaidy, S., Desai, P., Singh, G. K., and Nagori B. P. (2013). Journal of Pharmacognosy and Phytochemistry, 2(3), 170-175.

Jawaid, T., Argal, S., and Singh, S. (2011). Journal of Pharmacy Research, 4, 1138-1140.

Jeffrey, C. (2007). Families and Genera of Vascular Plants, 8, 61-87.

Jiang, H., Hu, J. R., Zhan, W. Q., Liu, X. (2009). Nat. Prod. Res., 23, 953–959.

Joo, D., Jeong, S., Lee, H. K., Shin, S. H., Choi, S. J., Kim, K., An I. S., Ku, J. E., Jeong, S. H and Cha, H. J. (2017). Biomedical Dermatology, 1(1), 1-6.

Joshi, A. R., and Joshi, K. (2007). Ethnobotanical leaflets, 2007(1), 1-16.

Kang, T. H., Yoon, G., Kang, I. A., Oh, H. N., Chae, J. I., and Shim, J. H. (2017). Phytotherapy Research, 31(12), 1858-1867.

Kaushik, D., Yadav, J., Kaushik, P., Sacher, D., and Rani, R. (2011). Zhong Xi Yi Jie He Xue Bao, 9(10), 1061-1065.

Khalifa, S., Elias, N., Farag, M. A., Chen, L., Saeed, A., Hegazy, M. F., Moustafa, M. S., Abd El-Wahed, A., Al-Mousawi, S. M., Musharraf, S. G., Chang, F. R., Iwasaki, A., Suenaga, K., Alajlani, M., Göransson, U., and El-Seedi, H. R. (2019). Marine drugs, 17(9), 491.

Khan, J.A., and Kumar, N. (2011). Journal of Pharmaceutical and Biomedical Sciences, 11, 1–3.

Khan, T., Ali, M., Khan, A., Nisar, P., Jan, S. A., Afridi, S., and Shinwari, Z. K. (2019). Biomolecules, 10(1), 1-30.

Kim, C., and Kim, B. (2018). Nutrients, 10(8), 1021.

Kim, J. A., Son, J. K., Chang, H. W., Jahng, Y., Kim, Y., Na, M., and Lee, S. H. (2008). Natural Product Communications, 3(10), 1934578X0800301014.

Kinoshita T., and Firman K. (1996). Phytochemistry, 42, 1207–1210

Kirira, P. G., Rukunga, G. M., Wanyonyi, A. W., Muregi, F. M., Gathirwa, J. W., Muthaura, C. N., Omar, S. A., Tolo, F., Mungai, G. M., and Ndiege, I. O. (2006). Journal of Ethnopharmacology, 106(3), 403–407

Koliopoulos, G., Pitarokili, D., Kioulos, E., Michaelakis, A., and Tzakou, O. (2010). Parasitology Research, 107(2), 327–335.

Koutsoulas, A., Čarnecká, M., Slanina, J., Tóth, J., and Slaninová, I. (2019). Molecules (Basel, Switzerland), 24(16), 2921

Kowarik, I., and Säumel, I. (2007). Perspectives in Plant Ecology, Evolution and Systematics, 8, 207–237.

Krup, V., Prakash, L. H., and Harini, A. (2013). Journal of Homeopathy and Ayurvedic Medicine, 2(133), 2167-1206.

Kumar Gupta, S., and Sharma, A. (2014). Journal of Pharmaceutical and Biological Sciences, 9, 124-129.

Kumar, N., Misra, P., Dube, A., Bhattacharya, S., Dikshit, M., and Ranade, S. (2010). Current Science, 99, 922–932.

Kumar, S., Singh, B., and Bajpai, V. (2021). Journal of Ethnopharmacology, 275, 114054.

Kundu, P., and Laskar, S. (2010). Phytochemistry Reviews, 9, 379–412.

Kurniawan, Y. S., Priyangga, K., Jumina, Pranowo, H. D., Sholikhah, E. N., Zulkarnain, A. K., Fatimi, H. A., and Julianus, J. (2021). Pharmaceuticals (Basel, Switzerland), 14(11), 1144.

Kyriakou, S., Tragkola, V., Plioukas, M., Anestopoulos, I., Chatzopoulou, P. S., Sarrou, E., Trafalis, D. T., Deligiorgi, M. V., Franco, R., Pappa, A., and Panayiotidis, M. I. (2021). Plants (Basel, Switzerland), 10(11), 2472.

Lahiri, S. C., and Dutta, N. K. (1967). Journal of the Indian Medical Association, 48(1), 1–11.

Lans, C. A. (2006). Journal Ethnobiol Ethnomedicine, 2, 45–55.

Lee, D. H., Ahn, S. S., Kim, J. B., Lim, Y., Lee, Y. H., and Shin, S. Y. (2018). International journal of molecular sciences, 19(6), 1640.

Leontaritou, P., Lamari, F. N., Papasotiropoulos, V., and Iatrou, G (2021). Phytochemistry, 191, 112900

Li, C. Y., Wang, Q., Wang, X., Li, G., Shen, S., and Wei, X. (2019). European Journal of Pharmacology, 858, 172463.

Liang, H. Z., Zhao, M.B., Tu, P.F., and Jiang Y. (2020). Biochemical Systematics and Ecology, 93, 104162.

Lin, X. F., Chen, K. J., Shi, H. K., Yu, L., Chen, J. S., and Fei, Y. (2017). Evidence-based Complementary and Alternative Medicine: eCAM, 2017, 3729547.

Liu, G., and Chu, H. (2018). Oncology Letters, 15(4), 5301–5305.

Liu, J. F., Lai, K. C., Peng, S. F., Maraming, P., Huang, Y. P., Huang, A. C., Chueh, F. S., Huang, W. W., and Chung, J. G. (2018). Molecules (Basel, Switzerland), 23(8), 2019.

Liu, M. H., Li, Y. F., and Chen, B. H. (2021). Plants (Basel, Switzerland), 10(10), 2129.

Liu, M. H., Li, Y. F., and Chen, B. H. (2021). Plants (Basel, Switzerland), 10(8), 1664.

Liu, Q., Shi, Y., Wang, Y., Lu, J., Cong, W., Luo, G., and Wang, Y. (2009). Talanta, 80(1), 84–91.

Liu, W., Liu, X., Pan, Z., Wang, D., Li, M., Chen, X., Zhou, L., Xu, M., Li, D., and Zheng, Q. (2019). Biomolecules, 9(7), 275.

Liu, X., Liu, L., Chen, K., Sun, L., Li, W., and Zhang, S. (2021). Journal of Cellular and Molecular Medicine, 25(4), 2228–2237.

Lo, C. Y., Liu, P. L., Lin, L. C., Chen, Y. T., Hseu, Y. C., Wen, Z. H., and Wang, H. M. (2013). The Scientific World Journal, 2013, 1-5.

Lo, C., Lai, T. Y., Yang, J. H., Yang, J. S., Ma, Y. S., Weng, S. W., Chen, Y. Y., Lin, J. G., and Chung, J. G. (2010). International Journal of Oncology, 37(2), 377–385.

Lo, C., Lai, T. Y., Yang, J. S., Yang, J. H., Ma, Y. S., Weng, S. W., Lin, H. Y., Chen, H. Y., Lin, J. G., and Chung, J. G. (2011). Melanoma Research, 21(4), 267–273.

Lv H.N., Wen R., Zhou Y., Zeng K.W., Li J., Guo X.Y., Tu P.F., and Jiang Y. (2015). Journal of Natural Products, 78, 2432–2439.

Lv, F., Li, X., and Wang, Y. (2022). Bioengineered, 13(4), 10931–10943.

Lyles, J. T., Luo, L., Liu, K., Jones, D. P., Jones, R. M., and Quave, C. L. (2021). Gut Microbes, 13(1), 1–6.

Ma, Y. S., Hsiao, Y. T., Lin, J. J., Liao, C. L., Lin, C. C., and Chung, J. G. (2017). Anticancer Research, 37(11), 6223–6234.

Mahmoud, A. B., Danton, O., Kaiser, M., Han, S., Moreno, A., Abd Algaffar, S., Khalid, S., Oh, W. K., Hamburger, M., and Mäser, P. (2020). Molecules (Basel, Switzerland), 25(12), 2825.

Maligan, J. M., Chairunnisa, F., and Wulan, S. N. (2019). Jurnal Ilmu Pangan Dan Hasil Pertanian, 2(2), 99–106.

Manci, R. N., Dauscher, M., Marchetti, M. A., Usatine, R., Rotemberg, V., Dusza, S. W., and Marghoob, A. A. (2022). Dermatology Practical and Conceptual, 12(2), e2022075.

Mann, S., Chaudhary, I. and Gupta, R. K. (2013). International Journal of Pharmacy and Life Sciences, 4(1), 2335-2339.

Manthey, J. A., Grohmann, K., and Guthrie, N. (2001). Current Medicinal Chemistry, 8, 135-153.

Mantso, T., Sfakianos, A. P., Atkinson, A., Anestopoulos, I., Mitsiogianni, M., Botaitis, S., Perente, S., Simopoulos, C., Vasileiadis, S., Franco, R., Pappa, A., and Panayiotidis, M. I. (2016). Anticancer Research, 36(12), 6303–6309.

Markowicz, J., Uram, Ł., Sobich, J., Mangiardi, L., Maj, P., and Rode, W. (2019). European Journal of Pharmacology, 863, 172678.

Mativandlela, S. P., Muthivhi, T., Kikuchi, H., Oshima, Y., Hamilton, C., Hussein, A. A., van der Walt, M. L., Houghton, P. J., and Lall, N. (2009). Journal of Natural Products, 72(12), 2169–2171

McGee, H. (2004). The science and lore of the kitchen. 2nd Edition,425-426.

Meihua, J. I. N., Bae, K., Chang, H. W., and Jong Keun, S. O. N. (2009). Biomolecules and Therapeutics,17(1), 86-91.

Miao, F., Yang, X. J., Zhou, L., Hu, H. J., Zheng, F., Ding, X. D., Sun, D. M., Zhou, C. D., and Sun, W. (2011). Natural Product Research, 25(9), 863–875.

Minaiyan, M., Ghanadian, S. M., and Hossaini, M. (2021). International Journal of Preventive Medicine, 12, 100.

Minteguiaga, M., Wallace, F., Basile, P., Ferreira, F., Olivaro, C., and Dellacassa, E. (2021). Medicinal and Aromatic Plants of South America, 2, 411-427.

Mitsiogianni, M., Amery, T., Franco, R., Zoumpourlis, V., Pappa, A., and Panayiotidis, M. I. (2018). Pharmacology and Therapeutics, 190, 187–201.

Mitsiogianni, M., Koutsidis, G., Mavroudis, N., Trafalis, D. T., Botaitis, S., Franco, R., Zoumpourlis, V., Amery, T., Galanis, A., Pappa, A., and Panayiotidis, M. I. (2019). Antioxidants (Basel, Switzerland), 8(4), 106

Mitsiogianni, M., Kyriakou, S., Anestopoulos, I., Trafalis, D. T., Deligiorgi, M. V., Franco, R., Pappa, A., and Panayiotidis, M. I. (2021). Antioxidants (Basel, Switzerland), 10(2), 1-14.

Mondin, C. A., Cervi, A. C, and Moreira, G. R. P. (2017). Rev Bras Biociências, 9(S1), 3–27.

Monji, F., Adaikan, P. G., Lau, L. C., Bin Said, B., Gong, Y., Tan, H. M., and Choolani, M. (2016). Journal of Ethnopharmacology, 193, 21–29.

Mu, X., Wang, L., Zhang, Z., Ge, R., Zhang, J., Liu, W., Mou, K., and Lv, S. (2021). Anti-Cancer Agents in Medicinal Chemistry, 21(5), 640–648.

Murad, H. M., Abdulameer, S. A., Aljuboory, D. S. A., Neamah, D. A., and Maktouf, A. H. (2020). Systematic Reviews in Pharmacy, 11(9), 841-846.

Nagori, K., Singh, M.K., Alexander, A., Kumar, T., Dewangan, D., Badwaik, H., and Tripathi, D. (2011). Journal of Pharmacy Research, 4, 2991–2997.

Naraghi, T., Emam, M., Ghamrizare, A., Damizadeh, G., and Shariat, A. (2012). Iranian Journal of Rangelands and Forests Plant Breeding and Genetic Research, 20(1), 134-144.

Nasr Bouzaiene, N., Chaabane, F., Sassi, A., Chekir-Ghedira, L., and Ghedira, K. (2016). Life sciences, 144, 80–85.

Nazar, S., Hussain, M. A., Khan, A., Muhammad, G., and Tahir, M. N. (2020). Arabian Journal of Chemistry, 13(1), 1901-1916.

Ndlovu, B., De Kock, M., Klaasen, J., and Rahiman, F. (2021). Scientia Pharmaceutica, 89(1), 1-11.

Nedi, T., Mekonnen, N., and Urga, K. (2004). Journal of Ethnopharmacology, 95(1), 57-61.

Ngulde, S. I., Sandabe, U. K., Abounader, R., Zhang, Y., and Hussaini, I. M. (2020). Advances in Pharmacological and Pharmaceutical Sciences, 2020, 3626879.

Ning, N., Liu, S., Liu, X., Tian, Z., Jiang, Y., Yu, N., Tan, B., Feng, H., Feng, X., and Zou, L. (2020). Journal of Cancer, 11(7), 1679–1692.

Oh, T. I., Jung, H. J., Lee, Y. M., Lee, S., Kim, G. H., Kan, S. Y., Kang, H., Oh, T., Ko, H. M., Kwak, K. C., and Lim, J. H. (2018). International Journal of Molecular Sciences, 19(10), 3149.

Okhuarobo, A., Falodun, J. E., Erharuyi, O., Imieje, V., Falodun, A., and Langer, P. (2014). Asian Pacific Journal of Tropical Disease, 4(3), 213–222.

Okunade, A. L., Bikoff, R. E., Casper, S. J., Oksman, A., Goldberg, D. E., and Lewis, W. H. (2003). Phytotherapy Research: PTR, 17(6), 675–677.

Padalia, R. C., Verma, R. S., Sundaresan, V., and Chanotiya, C. S. (2010). Chemistry and Biodiversity, 7(8), 2076–2087.

Pan, J., Yang, C., Jiang, Z., and Huang, J. (2019). Cancer Management and Research, 11, 1541–1549.

Park, E. H., Bae, W. Y., Eom, S. J., Kim, K. T., and Paik, H. D. (2017). Journal of Zhejiang University. Science. B, 18(2), 152–160.

Park, K. H., Joo, S. H., Seo, J. H., Kim, J., Yoon, G., Jeon, Y. J., Lee, M. H., Chae, J. I., Kim, W. K., and Shim, J. H. (2022). Biomolecules and Therapeutics, 30(1), 72–79.

Park, S. Y., Song, H., Sung, M. K., Kang, Y. H., Lee, K. W., and Park, J. H. (2014). International Journal of molecular Sciences, 15(7), 12698–12713.

Pavan, R., Jain, S., Shraddha, and Kumar, A. (2012). Biotechnology Research International, 2012, 976203.

Pay, A. (2016). BMJ Clinical Evidence, 2016, 1705.

Peng, X., Wang, Z., Liu, Y., Peng, X., Liu, Y., Zhu, S., Zhang, Z., Qiu, Y., Jin, M., Wang, R., Zhang, Q., and Kong, D. (2018). Life Sciences, 206, 35–44.

Pichichero, E., Cicconi, R., Mattei, M., and Canini, A. (2011). International Journal of Oncology, 38(2), 473-483.

Pratheeshkumar, P., Sheeja, K., and Kuttan, G. (2012). Immunopharmacology and Immunotoxicology, 34(1), 143–151.

Qureshi, K., Jahan, S., Amin, M., Akram, M. Z., and Jehan, R. (2014). The Pharma Innovation, 3(10, Part B), 51-54.

Rabe, S. T., Emami, S. A., Iranshahi, M., Rastin, M., Tabasi, N., and Mahmoudi, M. (2015). Asian Pacific Journal of Cancer Prevention, 16(3), 863-868.

Rahman, H. S., Rasedee, A., Yeap, S. K., Othman, H. H., Chartrand, M. S., Namvar, F., Abdul, A. B., and How, C. W. (2014). BioMed research international, 2014, 920742.

Rai, M. P., Thilakchand, K. R., Palatty, P. L., Rao, P., Rao, S., Bhat, H. P., and Baliga, M. S. (2011). Asian Pacific Journal of Cancer Prevention: APJCP, 12(9), 2149–2156.

Raissi, A., Arbabi, M., Roustakhiz, J., and Hosseini, M. (2016). Journal of HerbMed Pharmacology, 5(4), 125-130.

Rajagopal, S., Kumar, R. A., Deevi, D. S., Satyanarayana, C., and Rajagopalan, R. (2003). Journal of Experimental Therapeutics and Oncology, 3(3), 147–158.

Ramawat, K. G., and Goyal, S. (2008). Bioactive Molecules and Medicinal Plants, 19, 325-347.

Ramesh, K. V., Garima, S., Pradeep, S., Jha, K. K., and Khose, R. L. (2011). Der Pharmacia Sinica (Journal for Pharmaceutical Sciences), 2(1), 142-154.

Rao, Y. K., Lee, M. J., Chen, K., Lee, Y. C., Wu, W. S., and Tzeng, Y. M. (2011). Evidence-Based Complementary and Alternative Medicine: eCAM, 2011, 624375.

Ronse, A. C., Popper, Z. A., Preston, J. C., and Watson, M. F. (2010). Plant Systematics and Evolution, 287(1), 1-17.

Russo, A., Bruno, M., Avola, R., Cardile, V., and Rigano, D. (2020). Plants (Basel, Switzerland), 9(8), 1000.

Russo, A., Lombardo, L., Troncoso, N., Garbarino, J., and Cardile, V. (2009). Natural Product Communications, 4(12), 1707–1710.

Rwangabo, P. C., Claeys, M., Pieters, L., Corthout, J., Vanden Berghe, D. A., and Vlietinck, A. J. (1988). Journal of Natural Products, 51(5), 966–968.

Saeio, K., Chaiyana, W., and Okonogi, S. (2011). Drug Discoveries and Therapeutics, 5(3), 144–149.

Saginala, K., Barsouk, A., Aluru, J. S., Rawla, P., and Barsouk, A. (2021). Medical Sciences (Basel, Switzerland), 9(4), 1-9.

Sak, K., Nguyen, T. H., Ho, V. D., Do, T. T., and Raal, A. (2017). Cogent Medicine, 4(1), 1333218

Sa-Ngiamsuntorn, K., Suksatu, A., Pewkliang, Y., Thongsri, P., Kanjanasirirat, P., Manopwisedjaroen, S., Charoensutthivarakul, S., Wongtrakoongate, P., Pitiporn, S., Chaopreecha, J., Kongsomros, S., Jearawuttanakul, K., Wannalo, W., Khemawoot, P., Chutipongtanate, S., Borwornpinyo, S., Thitithanyanont, A., and Hongeng, S. (2021). Journal of Natural Products, 84(4), 1261–1270.

Sass, C. Bojin, F., Heges, A., Galuscan, A., and Paunescu, V. (2012). Fiziol. Physiol, 22, 30-33.

Serafim, T. L., Matos, J. A., Sardão, V. A., Pereira, G. C., Branco, A. F., Pereira, S. L., Parke, D., Perkins, E. L., Moreno, A. J., Holy, J., and Oliveira, P. J. (2008). Biochemical Pharmacology, 76(11), 1459–1475.

Sevindik, N., and Rencuzogullari, E. (2014). Drug and Chemical Toxicology, 37(3), 295–302.

Shahraki, M. R., Badini, F., Shahraki, E., Shahraki, A. R., and Dashipour, A. (2020). Nutrition and Food Sciences Research, 7(1), 25-31.

Shamilov, A. A., Bubenchikova, V. N., Chernikov, M. V., Pozdnyakov, D. I., Garsiya, E. R., and Larsky, M. V. (2021). Journal of Excipients and Food Chemicals, 12(3), 49-66.

Shawi, A. A., Rasul, A., Khan, M., Iqbal, F., and Tonghui, M. (2011). African Journal of Pharmacy and Pharmacology, 5, 582–588.

Sheeja, K., Guruvayoorappan, C., and Kuttan, G. (2007). International Immunopharmacology, 7, 211–221.

Shen, H., Zeng, G., Sun, B., Cai, X., Bi, L., Tang, G., and Yang, Y. (2015). Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(6), 4825–4831.

Shinwari, Z. K. (2010). Journal of Medicinal Plants Research, 4(3), 161- 176.

Shiue, Y. W., Lu, C. C., Hsiao, Y. P., Liao, C. L., Lin, J. P., Lai, K. C., Yu, C. C., Huang, Y. P., Ho, H. C., and Chung, J. G. (2016). The American journal of Chinese medicine, 44(3), 637–661

Shukla, Y., and Singh, M. (2007). Cancer preventive properties of zinger: A brief review. Food and Chemical Toxicology, 45(5), 683–690.

Si, L., Yan, X., Hao, W., Ma, X., Ren, H., Ren, B., Li, D., Dong, Z., and Zheng, Q. (2018). Oncology Reports, 39(5), 2160–2170.

Silva, V., Cerqueira, F., Nazareth, N., Medeiros, R., Sarmento, A., Sousa, E., and Pinto, M. (2019). Pharmaceuticals (Basel, Switzerland), 12(2), 1-13.

Singh, D., and Singh, R.K. (2011). Indian Journal of Traditional Knowledge, 10(1), 146-155.

Singh, P., Mishra, G., Srivastava, S., Jha, K. K., and Khosa, R. L. (2011). Der Pharmacia Lettre, 3(2), 71-82.

Singh, T., and Katiyar, S. K. (2011). PloS one, 6(10), e25224.

Singh, T., Vaid, M., Katiyar, N., Sharma, S., and Katiyar, S. K. (2011). Carcinogenesis, 32(1), 86–92.

Sivakumar, R., and Kamachandran, N. A. G. (1991). Journal of the Indian Chemical Society, 68(9), 531-532.

Sladonja, B., Sušek, M., and Guillermic, J. (2015). Environmental Management, 56(4), 1009-1034.

Slominski, A., Wortsman, J., Carlson, A. J., Matsuoka, L. Y., Balch, C. M., and Mihm, M. C. (2001). Archives of pathology and laboratory medicine, 125(10), 1295–1306.

Song, X., Li, Y., Zhang, H., and Yang, Q. (2015). Oncology Reports, 34(1), 12–21.

Srivastava, J. K., and Gupta, S. (2007). Journal of Agricultural and Food Chemistry, 55(23), 9470–9478.

Srivastava, J. K., and Gupta, S. (2009). Molecular and Cellular Pharmacology, 1(3), 138.

Srivastava, N. S., and Srivastava, R. (2019). Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 52, 117–128.

Strimpakos, A. S., and Sharma, R. A. (2008). Antioxidants and Redox Signaling, 10(3), 511–545.

Su, D. M., Zhang, Q., Wang, X., He, P., Zhu, Y. J., Zhao, J., Rennert, O. M., and Su, Y. A. (2009). Molecular Cancer Therapeutics, 8(5), 1292–1304.

Su, D., Jiang, B., Yang, Y., Miao, Y., Fu, Q., and Zhang, F. (2020). BioMed Research International, 2020, 8163839.

Svensson, L., Sekwati-Monang, B., Lutz, D. L., Schieber, A., and Gänzle, M. G. (2010). Journal of Agricultural and Food Chemistry, 58(16), 9214–9220.

Tai, Y., Ling, C., Wang, H., Yang, L., She, G., Wang, C., Yu, S., Chen, W., Liu, C., and Wan, X. (2019). Journal of Agricultural and Food Chemistry, 67(36), 10235–10244.

Teillet, F., Boumendjel, A., Boutonnat, J., and Ronot, X. (2008). Medicinal Research Reviews, 28, 715-745.

Thaichinda, S., Nararatwanchai, T., Tancharoen, S., Kanekura, T., and Higashi, Y. A. (2018). International Conference on Digital Arts, Media and Technology (ICDAMT), 2018, 301-304.

Thaichinda, S., Tancharoen, S., Kanekura, T., Higashi, Y., Dararat, P., Kikuchi, K., and Nararatwanchai, T. (2020). Natural Product Communications, 15(5), 1934578X20926889.

Thuncharoen, W., Chulasiri, M., Nilwarangkoon, S., Nakamura, Y., and Watanapokasin, R. (2013). Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96 Suppl 1, S60–S64.

Tilak, J. C., Banerjee, M., Mohan, H., and Devasagayam, T. P. A. (2004). Phytotherapy Research, 18, 798-804.

Tolo, F. M., Rukunga, G. M., Muli, F. W., Njagi, E. N., Njue, W., Kumon, K., Mungai, G. M., Muthaura, C. N., Muli, J. M., Keter, L. K., Oishi, E., and Kofi-Tsekpo, M. W. (2006). Journal of Ethnopharmacology, 104(1-2), 92–99.

Tong, L., Chuang, C. C., Wu, S., and Zuo, L. (2015). Cancer Letters, 367(1), 18–25.

Tsai, M. L., Lin, C. D., Khoo, K. A., Wang, M. Y., Kuan, T. K., Lin, W. C., Zhang, Y. N., and Wang, Y. Y. (2017). Molecules (Basel, Switzerland), 22(12), 2154.

Tuzimski, T., Petruczynik, A., Plech, T., Kaproń, B., Makuch-Kocka, A., Szultka-Młyńska, M., Misiurek, J., and Buszewski, B. (2021). Molecules (Basel, Switzerland), 26(6), 1738.

Uddin, Z., Shad, A. A., Bakht, J., Ullah, I., and Jan, S. (2015). Pakistan Journal of Pharmaceutical Sciences, 28(5), 1699–1704.

Vieito, C.; Fernandes, É.; Velho, M. V.; Pires, P. (2018). Chemical Engineering Transactions, 64, 127-132.

Wang, F., Ma, H., Liu, Z., Huang, W., Xu, X., and Zhang, X. (2017). Biomedicine and Pharmacotherapy, 92, 672–680.

Wang, X., Zhang, H., Chen, L., Shan, L., Fan, G., and Gao, X. (2013). Journal of Ethnopharmacology, 150(3), 781–790.

Wangteeraprasert, R., and Likhitwitayawuid, K. (2009). Helvetica Chimica Acta, 92(6), 1217-1223.

Woo, J. S., Choo, G. S., Yoo, E. S., Kim, S. H., Lee, J. H., Han, S. H., Kim, H. J., Jung, S. H., Park, Y. S., Kim, B. S., Kim, S. K., Park, B. K., Cho, S. D., Nam, J. S., Choi, C. S., Che, J. H., and Jung, J. Y. (2020). Molecular Medicine Reports, 22(6), 4877–4889.

Woo, S. M., Choi, W. R., Lee, D. R., Kim, H. S., Yi, C., Kim, K. H., Kim, H. L., Cheng, J., Le, B., Yang, S. H. and Suh, J. W. (2019). European Journal of Integrative Medicine, 25, 85-91.

Wu, Y. J., Su, T. R., Chang, C. I., Chen, C. R., Hung, K. F., and Liu, C. (2020). International Journal of Molecular Sciences, 21(10), 3737.

Wu, Z. Y., Lien, J. C., Huang, Y. P., Liao, C. L., Lin, J. J., Fan, M. J., Ko, Y. C., Hsiao, Y. P., Lu, H. F., and Chung, J. G. (2016). Molecules (Basel, Switzerland), 21(3), 384.

Xiao-yu, C. H. E. N., Ying, C. H. E. N., Chuan-jun, Q. U., De-fang, L. I., and Qiu-sheng, Z. H. E. N. G. (2019). Natural Product Research and Development, 31(8), 1350.

Xu, J., Wei, K., Zhang, G., Lei, L., Yang, D., Wang, W., Han, Q., Xia, Y., Bi, Y., Yang, M., and Li, M. (2018). Journal of Ethnopharmacology, 225, 18–30.

Xu, Y. J., Zhao, D. X., Fu, C. X., Cheng, L. Q., Wang, N. F., Han, L. J., and Ma, F. S. (2009). Natural product Research, 23(18), 1689–1698.

Yahya, Y. F., Fantoni, O. J. J., Budiamal, S., and Toruan, T. L. (2022). Bioscientia Medicina: Journal of Biomedicine and Translational Research, 6(6), 1896-1907.

Yang, A. L., Hu, Z. D., and Tu, P. F. (2015). Journal of Chinese Materia Medica, 40(24), 4805-4810.

Yang, J., Xiao, P., Sun, J., and Guo, L. (2018). Journal of B.U.ON.: official Journal of the Balkan Union of Oncology, 23(1), 218–223.

Yang, S., Zhang, Y., Luo, Y., Xu, B., Yao, Y., and Deng, Y. (2018b). Biomedicine and Pharmacotherapy, 103, 101–110.

Yang, T. Y., Wu, M. L., Chang, C. I., Liu, C. I., Cheng, T. C., and Wu, Y. J. (2018a). International Journal of Molecular Sciences, 19(8), 2152.

Yang, X. L., Yuan, Y. L., Zhang, D. M., Li, F., and Ye, W. C. (2014). Natural Product Research, 28(18), 1432–1437.

Yang, Y., Jin, P., Zhang, X., Ravichandran, N., Ying, H., Yu, C., Ying, H., Xu, Y., Yin, J., Wang, K., Wu, M., and Du, Q. (2017). Journal of Biomedical Nanotechnology, 13(7), 805-814.

Yao, X., Jiang, W., Yu, D., and Yan, Z., (2019). Food and Function, 10(2), 703–712.

Yoon, G., Kang, B. Y., and Cheon, S. H. (2007). Archives of Pharmacal Research, 30(3), 313–316.

You, C. X., Zhang, K., Li, X., Liu, J., Zhang, W. J., and Yu, X. X. (2021). Molecules (Basel, Switzerland), 26(5), 1284.

Yusoff, M. M., Ibrahim, H., and Hamid, N. A. (2011). Chemistry and Biodiversity, 8(5), 916-923.

Zeng, N., Qiu, H., Lian, X., Ren, Y., Xu, Y., Wu, Y., Tang, H. and Wang, H. (2017). Tropical Journal of Pharmaceutical Research, 16(6), 1231-1237.

Zhang, D., Yuan, W., Zhang, B., Hong, E. K., Shi, P., Yang, Z., Zhang, Y., and Wang, H. (2020b). Pakistan Journal of Pharmaceutical Sciences, 33(2), 669–674.

Zhang, D.D., Bai, M., Yan, Z.Y., Huang, X.X., and Song, S.J. (2020a). Biochemical Systematics and Ecology, 93, 104174

Zhang, F., Zhang, Z., and Liu, Z. (2013). Acta Histochemica, 115(7), 705–711.

Zhang, L., Yan, B., Meng, S., Zhou, L., Xu, Y., Du, W., and Shan, L. (2020c). Frontiers in Pharmacology, 11, 1317.

Zhang, Q. Q., Zhou, D. L., Ding, Y., Liu, H. Y., Lei, Y., Fang, H. Y., Gu, Q. L., He, X. D., Qi, C. L., Yang, Y., Lan, T., Li, J. C., Gong, P., Wu, X. Y., Yang, X., Li, W. D., and Wang, L. J. (2014). Melanoma Research, 24(6), 545–555.

Zhang, W., Tang, B., Huang, Q., and Hua, Z. (2013). Journal of Cellular Biochemistry, 114(1), 152-161.

Zhang, Y. P., Li, Y. Q., Lv, Y. T., and Wang, J. M. (2015). Genet Mol Res, 14(1), 1056-1067.

Zhao, K., Li, J., Zhang, X., Chen, Q., Liu, M., Ao, X., and Penttinen, P. (2018). Scientific Reports, 8(1), 1-13.

Zheng, Y., Wang, K., Wu, Y., Chen, Y., Chen, X., Hu, C. W., and Hu, F. (2018). Cancer Letters, 431, 31–42.

Zhou, C., Chen, X., Zeng, W., Peng, C., Huang, G., Li, X., Ouyang, Z., Luo, Y., Xu, X., Xu, B., Wang, W., He, R., Zhang, X., Zhang, L., Liu, J., Knepper, T. C., He, Y., and McLeod, H. L. (2016). Oncotarget, 7(42), 68314–68327.

Zhu, J., Chen, L., Qi, Y., Feng, J., Zhu, L., Bai, Y., and Wu, H. (2018). Molecular Vision, 24, 315–325.

Zia-Ul-Haq, M., Cavar, S., Qayum, M., Imran, I., and de Feo, V. (2011). International Journal of Molecular Sciences, 12(12), 8846–8861.




DOI: https://doi.org/10.17509/ijost.v7i3.51325

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